Do I need to remove the tonneau to open my tailgate?

No. The tri-fold design lets you collapse the rear panel without touching the clamps, so you can drop the gate freely whenever you need it.

Will this work with my bed rails or toolbox?

The mounting system is compatible with aftermarket bed rails, but test-fit before final installation. If you have a bed toolbox, confirm clearance at the fold points first.

What kind of prep or sealant should I use before installing?

Clean the clamp mounting surface on your bed rails to remove dust and debris, then install dry. No sealant needed — the fabric provides weather protection at the seams.